• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYST1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-KAT8 antibody (101-150) (STJ94179)

SKU:
STJ94179

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Histone acetyltransferase KAT8 (101-150) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KAT8
Gene ID: 84148
Uniprot ID: KAT8_HUMAN
Immunogen Region: 101-150
Specificity: MOF Polyclonal Antibody detects endogenous levels of MOF protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MYST1. AA range:101-150
Post Translational Modifications Autoacetylation at Lys-274 is required for binding histone H4 with high affinity and for proper function.
Function Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.
Protein Name Histone Acetyltransferase Kat8
Lysine Acetyltransferase 8
Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 1
Myst-1
Hmof
Database Links Reactome: R-HSA-3214847
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone Acetyltransferase Kat8 antibody
Anti-Lysine Acetyltransferase 8 antibody
Anti-Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 1 antibody
Anti-Myst-1 antibody
Anti-Hmof antibody
Anti-KAT8 antibody
Anti-MOF antibody
Anti-MYST1 antibody
Anti-PP7073 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance