| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Kappa Light Chain for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | CH15 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Tissue culture supernatant with 15mM Sodium azide |
| Concentration: | >=125 mg/L |
| Dilution Range: | IHC-P 1:200 |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Prokaryotic recombinant protein corresponding to 106 amino acids of the human kappa light chain molecule. |
| Background | Immunoglobulins are polypeptides and comprise five major classes; immunoglobulin G (IgG) , IgA, IgM, IgD and IgE. Each immunoglobulin consists of two identical heavy (H) chains and two identical light (L) chains.These are also subdivided into sub classes eg IgG1. There are two classes of light chain; kappa and lambda. The ratio of kappa chains and lambda chains varies between Ig classes and sub classes, but is also species specific. In humans, approximately 60 percent of light chains are kappa. However, in any particular immunoglobulin molecule the light chain will be either kappa or lambda. B cells contain either kappa or lambda mRNA. |
Information sourced from Uniprot.org

