| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Kalirin (810-890 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KALRN |
| Gene ID: |
8997 |
| Uniprot ID: |
KALRN_HUMAN |
| Immunogen Region: |
810-890 aa |
| Specificity: |
Duo Polyclonal Antibody detects endogenous levels of Duo protein. |
| Immunogen: |
Synthesized peptide derived from Duo at the amino acid range 810-890 |
| Post Translational Modifications | Autophosphorylated. |
| Function | Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. |
| Protein Name | KalirinHuntingtin-Associated Protein-Interacting ProteinProtein DuoSerine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-3928662Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-5687128Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmCytoskeletonAssociated With The Cytoskeleton |
| Alternative Antibody Names | Anti-Kalirin antibodyAnti-Huntingtin-Associated Protein-Interacting Protein antibodyAnti-Protein Duo antibodyAnti-Serine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain antibodyAnti-KALRN antibodyAnti-DUET antibodyAnti-DUO antibodyAnti-HAPIP antibodyAnti-TRAD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
