| Short Description : | Rabbit monoclonal JunD (100-200) antibody for use in WB, IP, ELISA, ChIP and CUT&Tag in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IP/ELISA/ChIP/CUT&Tag |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:6000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.ChIP:5 Mu g ant |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JUND |
| Gene ID: | 3727 |
| Uniprot ID: | JUND_HUMAN |
| Immunogen Region: | 100-200 |
| Immunogen Sequence: | SPELERLIIQSNGLVTTTPT SSQFLYPKVAASEEQEFAEG FVKALEDLHKQNQLGAGAAA AAAAAAAGGPSGTATGSAPP GELAPAAAAPEAPVYANLSS Y |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human JunD (P17535). |
| Post Translational Modifications | Phosphorylated by MAP kinases MAPK8 and MAPK10.phosphorylation is inhibited in the presence of MEN1. |
| Function | Transcription factor binding AP-1 sites. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGAGCTCA-5' and enhancing their transcriptional activity. |
| Protein Name | Transcription Factor JundTranscription Factor Ap-1 Subunit Jund |
| Database Links | Reactome: R-HSA-9018519Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Jund antibodyAnti-Transcription Factor Ap-1 Subunit Jund antibodyAnti-JUND antibody |
Information sourced from Uniprot.org
