| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JUND |
| Gene ID: | 3727 |
| Uniprot ID: | JUND_HUMAN |
| Immunogen Region: | 1-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human JunD (NP_005345.3). |
| Immunogen Sequence: | METPFYGDEALSGLGGGASG SGGSFASPGRLFPGAPPTAA AGSMMKKDALTLSLSEQVAA ALKPAAAPPPTPLRADGAPS AAPPDGLLASPDLGLLKLAS PELERLIIQSNGLVTTTPTS SQFLYPKVAASEEQEFAEGF VKALEDLHKQNQLGAGAAAA AAAAAAGGPSGTATGSAPPG ELAPAAAAPE |
| Post Translational Modifications | Phosphorylated by MAP kinases MAPK8 and MAPK10.phosphorylation is inhibited in the presence of MEN1. |
| Function | Transcription factor binding AP-1 sites. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGAGCTCA-5' and enhancing their transcriptional activity. |
| Protein Name | Transcription Factor JundTranscription Factor Ap-1 Subunit Jund |
| Database Links | Reactome: R-HSA-9018519Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Jund antibodyAnti-Transcription Factor Ap-1 Subunit Jund antibodyAnti-JUND antibody |
Information sourced from Uniprot.org