Anti-JPH1 antibody (STJA0008631)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human JPH1
General Information
| Short Description | Rabbit polyclonal anti-Junctophilin-1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JPH1 |
| Gene ID | 56704 |
| Uniprot ID | JPH1_HUMAN |
| Immunogen | Synthesized peptide derived from human JPH1 |
| Specificity | This antibody detects endogenous levels of JPH1 at Human, Mouse |
Additional Info
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes. |
| Protein Name | Junctophilin-1Jp-1Junctophilin Type 1 |
| Database Links | |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinSarcoplasmic Reticulum MembraneLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic/Sarcoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma MembraneIn Skeletal Muscle CellsIt Is Predominantly Localized At The Junction Of The A And I Bands |
| Alternative Antibody Names | Anti-Junctophilin-1 antibodyAnti-Jp-1 antibodyAnti-Junctophilin Type 1 antibodyAnti-JPH1 antibodyAnti-JP1 antibody |
Information sourced from Uniprot.org