| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JMJD8 |
| Gene ID: | 339123 |
| Uniprot ID: | JMJD8_HUMAN |
| Immunogen Region: | 1-285 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human JMJD8 (NP_001005920.2). |
| Immunogen Sequence: | MAGGWAQGSRRAARLPEGGR LMAPASRLLALWALAAVALP GSGAEGDGGWRPGGPGAVAE EERCTVERRADLTYAEFVQQ YAFVRPVILQGLTDNSRFRA LCSRDRLLASFGDRVVRLST ANTYSYHKVDLPFQEYVEQL LHPQDPTSLGNDTLYFFGDN NFTEWASLFRHYSPPPFGLL GTAPAYSFGIAGAGSGVPFH WHGPGYSEVIYGRKRWFLYP PEKTPEFHPNKTTLAWLRD |
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as a positive regulator of TNF-induced NF-kappa-B signaling. Regulates angiogenesis and cellular metabolism through interaction with PKM. |
| Protein Name | Jmjc Domain-Containing Protein 8Jumonji Domain-Containing Protein 8 |
| Cellular Localisation | Endoplasmic Reticulum LumenCytoplasm |
| Alternative Antibody Names | Anti-Jmjc Domain-Containing Protein 8 antibodyAnti-Jumonji Domain-Containing Protein 8 antibodyAnti-JMJD8 antibodyAnti-C16orf20 antibodyAnti-PP14397 antibody |
Information sourced from Uniprot.org