• Immunohistochemistry analysis of JMJD1C in paraffin-embedded mouse spinal cord using JMJD1C Rabbit polyclonal antibody (STJ11103184) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of JMJD1C in paraffin-embedded human esophageal using JMJD1C Rabbit polyclonal antibody (STJ11103184) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of JMJD1C in paraffin-embedded rat brain using JMJD1C Rabbit polyclonal antibody (STJ11103184) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using JMJD1C Rabbit polyclonal antibody (STJ11103184) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-JMJD1C antibody (354-448) (STJ11103184)

SKU:
STJ11103184

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-JMJD1C (354-448) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: JMJD1C
Gene ID: 221037
Uniprot ID: JHD2C_HUMAN
Immunogen Region: 354-448
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 354-448 of human JMJD1C (NP_116165.1).
Immunogen Sequence: KPEEDEKKLNMKRLRTDNVS DFSESSDSENSNKRIIDNSS EQKPENELKNKNTSKINGEE GKPHNNEKAGEETLKNSQPP WDQIQEDKKHEEAEK
Function Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
Protein Name Probable Jmjc Domain-Containing Histone Demethylation Protein 2c
Jumonji Domain-Containing Protein 1c
Thyroid Receptor-Interacting Protein 8
Tr-Interacting Protein 8
Trip-8
Database Links Reactome: R-HSA-983231
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Probable Jmjc Domain-Containing Histone Demethylation Protein 2c antibody
Anti-Jumonji Domain-Containing Protein 1c antibody
Anti-Thyroid Receptor-Interacting Protein 8 antibody
Anti-Tr-Interacting Protein 8 antibody
Anti-Trip-8 antibody
Anti-JMJD1C antibody
Anti-JHDM2C antibody
Anti-KIAA1380 antibody
Anti-TRIP8 antibody

Information sourced from Uniprot.org

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