| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JMJD1C |
| Gene ID: | 221037 |
| Uniprot ID: | JHD2C_HUMAN |
| Immunogen Region: | 354-448 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 354-448 of human JMJD1C (NP_116165.1). |
| Immunogen Sequence: | KPEEDEKKLNMKRLRTDNVS DFSESSDSENSNKRIIDNSS EQKPENELKNKNTSKINGEE GKPHNNEKAGEETLKNSQPP WDQIQEDKKHEEAEK |
| Function | Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes. |
| Protein Name | Probable Jmjc Domain-Containing Histone Demethylation Protein 2cJumonji Domain-Containing Protein 1cThyroid Receptor-Interacting Protein 8Tr-Interacting Protein 8Trip-8 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Probable Jmjc Domain-Containing Histone Demethylation Protein 2c antibodyAnti-Jumonji Domain-Containing Protein 1c antibodyAnti-Thyroid Receptor-Interacting Protein 8 antibodyAnti-Tr-Interacting Protein 8 antibodyAnti-Trip-8 antibodyAnti-JMJD1C antibodyAnti-JHDM2C antibodyAnti-KIAA1380 antibodyAnti-TRIP8 antibody |
Information sourced from Uniprot.org
