| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | JCHAIN |
| Gene ID: | 3512 |
| Uniprot ID: | IGJ_HUMAN |
| Immunogen Region: | 23-159 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-159 of human JCHAIN (NP_653247.1). |
| Immunogen Sequence: | QEDERIVLVDNKCKCARITS RIIRSSEDPNEDIVERNIRI IVPLNNRENISDPTSPLRTR FVYHLSDLCKKCDPTEVELD NQIVTATQSNICDEDSATET CYTYDRNKCYTAVVPLVYGG ETKMVETALTPDACYPD |
| Function | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component. |
| Protein Name | Immunoglobulin J ChainJoining Chain Of Multimeric Iga And Igm |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Immunoglobulin J Chain antibodyAnti-Joining Chain Of Multimeric Iga And Igm antibodyAnti-JCHAIN antibodyAnti-IGCJ antibodyAnti-IGJ antibody |
Information sourced from Uniprot.org