Anti-JAG1 antibody (C-Term) (STJ72591)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-JAG1 (C-Term) is suitable for use in ELISA, Immunofluorescence and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IF/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.IHC: In paraffin embedded Human Kidney shows membrane staining in the epithelial cells of convoluted tubules. Recommended concentration, 2-4µg/ml.IF: Strong expression of the protein s |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | JAG1 |
| Gene ID | 182 |
| Uniprot ID | JAG1_HUMAN |
| Accession Number | NP_000205.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | TNKQDNRDLESAQS |
Additional Info
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
| Protein Name | Protein Jagged-1Jagged1Hj1Cd Antigen Cd339 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-8941856Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9013507Reactome: R-HSA-9013700Reactome: R-HSA-9831926 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Protein Jagged-1 antibodyAnti-Jagged1 antibodyAnti-Hj1 antibodyAnti-Cd Antigen Cd339 antibodyAnti-JAG1 antibodyAnti-JAGL1 antibody |
Information sourced from Uniprot.org