Anti-JAG1 antibody (C-Term) (STJ72591)

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STJ72591-100
€375.00
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Short Description :Goat polyclonal antibody anti-JAG1 (C-Term) is suitable for use in ELISA, Immunofluorescence and Immunohistochemistry research applications.
Applications:Pep-ELISA/IF/IHC
Host:Goat
Reactivity:Human/Mouse/Rat/Dog/Pig/Cow
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:8000.
IHC: In paraffin embedded Human Kidney shows membrane staining in the epithelial cells of convoluted tubules. Recommended concentration, 2-4µg/ml.
IF: Strong expression of the protein s
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:JAG1
Gene ID:182
Uniprot ID:JAG1_HUMAN
Accession Number:NP_000205.1
Immunogen Region:C-Term
Immunogen Sequence:TNKQDNRDLESAQS
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Protein Name Protein Jagged-1
Jagged1
Hj1
Cd Antigen Cd339
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-8941856
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9013507
Reactome: R-HSA-9013700
Reactome: R-HSA-9831926
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Protein Jagged-1 antibody
Anti-Jagged1 antibody
Anti-Hj1 antibody
Anti-Cd Antigen Cd339 antibody
Anti-JAG1 antibody
Anti-JAGL1 antibody

Information sourced from Uniprot.org