Anti-JADE1 antibody (STJA0007439)

SKU:
STJA0007439
$64.80 - $340.20
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Protein Jade-1 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: JADE1
Gene ID: 79960
Uniprot ID: JADE1_HUMAN
Specificity: This antibody detects endogenous levels of PHF17 at Human, Mouse
Immunogen: Synthesized peptide derived from human PHF17
Function Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling.at least in part, cooperates with NPHP4 in this function.
Protein Name Protein Jade-1
Jade Family Phd Finger Protein 1
Phd Finger Protein 17
Database Links Reactome: R-HSA-3214847
Cellular Localisation Nucleus
Chromosome
Cytoplasm
Cytoskeleton
Cilium Basal Body
Localizes To The Ciliary Transition Zone
Alternative Antibody Names Anti-Protein Jade-1 antibody
Anti-Jade Family Phd Finger Protein 1 antibody
Anti-Phd Finger Protein 17 antibody
Anti-JADE1 antibody
Anti-KIAA1807 antibody
Anti-PHF17 antibody

Information sourced from Uniprot.org

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