| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IVD |
| Gene ID: | 3712 |
| Uniprot ID: | IVD_HUMAN |
| Immunogen Region: | 33-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_002216.2). |
| Immunogen Sequence: | HSLLPVDDAINGLSEEQRQL RQTMAKFLQEHLAPKAQEID RSNEFKNLREFWKQLGNLGV LGITAPVQYGGSGLGYLEHV LVMEEISRASGAVGLSYGAH SNLCINQLVRNGNEAQKEKY LPKLISGEYIGALAMSEPNA GSDVVSMKLKAEKKGNHYIL NGNKFWIT |
| Function | Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway. To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA. |
| Protein Name | Isovaleryl-Coa Dehydrogenase - MitochondrialIvdButyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Isovaleryl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Ivd antibodyAnti-Butyryl-Coa Dehydrogenase antibodyAnti-IVD antibody |
Information sourced from Uniprot.org