| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Intersectin-2 (1125-1175 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITSN2 |
| Gene ID: | 50618 |
| Uniprot ID: | ITSN2_HUMAN |
| Immunogen Region: | 1125-1175 aa |
| Specificity: | ITSN2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 1125-1175 |
| Function | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. |
| Protein Name | Intersectin-2Sh3 Domain-Containing Protein 1bSh3p18Sh3p18-Like Wasp-Associated Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9013420 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Intersectin-2 antibodyAnti-Sh3 Domain-Containing Protein 1b antibodyAnti-Sh3p18 antibodyAnti-Sh3p18-Like Wasp-Associated Protein antibodyAnti-ITSN2 antibodyAnti-KIAA1256 antibodyAnti-SH3D1B antibodyAnti-SWAP antibody |
Information sourced from Uniprot.org