Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Intersectin-2 (1125-1175 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ITSN2 |
Gene ID: |
50618 |
Uniprot ID: |
ITSN2_HUMAN |
Immunogen Region: |
1125-1175 aa |
Specificity: |
ITSN2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from part of the human protein at the amino acid range 1125-1175 |
Function | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. |
Protein Name | Intersectin-2Sh3 Domain-Containing Protein 1bSh3p18Sh3p18-Like Wasp-Associated Protein |
Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9013420 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Intersectin-2 antibodyAnti-Sh3 Domain-Containing Protein 1b antibodyAnti-Sh3p18 antibodyAnti-Sh3p18-Like Wasp-Associated Protein antibodyAnti-ITSN2 antibodyAnti-KIAA1256 antibodyAnti-SH3D1B antibodyAnti-SWAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance