| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inosine triphosphate pyrophosphatase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ITPA |
| Gene ID: |
3704 |
| Uniprot ID: |
ITPA_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ITPA at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ITPA |
| Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
| Protein Name | Inosine Triphosphate PyrophosphataseItpaseInosine TriphosphataseNon-Canonical Purine Ntp PyrophosphataseNon-Standard Purine Ntp PyrophosphataseNucleoside-Triphosphate DiphosphataseNucleoside-Triphosphate PyrophosphataseNtpasePutative Oncogene Protein Hlc14-06-P |
| Database Links | Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Inosine Triphosphate Pyrophosphatase antibodyAnti-Itpase antibodyAnti-Inosine Triphosphatase antibodyAnti-Non-Canonical Purine Ntp Pyrophosphatase antibodyAnti-Non-Standard Purine Ntp Pyrophosphatase antibodyAnti-Nucleoside-Triphosphate Diphosphatase antibodyAnti-Nucleoside-Triphosphate Pyrophosphatase antibodyAnti-Ntpase antibodyAnti-Putative Oncogene Protein Hlc14-06-P antibodyAnti-ITPA antibodyAnti-C20orf37 antibodyAnti-My049 antibodyAnti-OK antibodyAnti-SW-cl.9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
