• Western blot analysis of extracts from A549, using Integrin Beta 5/ITGB5 Rabbit monoclonal antibody (STJ11105106) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-ITGB5 antibody (24-490 aa) [S5106RM] (STJ11105106)

SKU:
STJ11105106

£129.50 - £574.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: S5106RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:4000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITGB5
Gene ID: 3693
Uniprot ID: ITB5_HUMAN
Immunogen Region: 24-490 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 24-490 of human Integrin Beta 5/ITGB5. (NP_002204.2).
Immunogen Sequence: GLNICTSGSATSCEECLLIH PKCAWCSKEDFGSPRSITSR CDLRANLVKNGCGGEIESPA SSFHVLRSLPLSSKGSGSAG WDVIQMTPQEIAVNLRPGDK TTFQLQVRQVEDYPVDLYYL MDLSLSMKDDLDNIRSLGTK LAEEMRKLTSNFRLGFGSFV DKDISPFSYTAPRYQTNPCI GYKLFPNCVPSFGFRHLLPL TDRVDSFNEEVRKQRVSRNR DAPEGGFDAVLQAAVCKEK
Function Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.
Protein Name Integrin Beta-5
Database Links Reactome: R-HSA-1236973
Reactome: R-HSA-2129379
Reactome: R-HSA-216083
Reactome: R-HSA-2173789
Reactome: R-HSA-3000170
Reactome: R-HSA-3000178
Reactome: R-HSA-445355
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Beta-5 antibody
Anti-ITGB5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance