Anti-ITGAX antibody (146-342) (STJ111096)

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STJ111096
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITGAX
Gene ID: 3687
Uniprot ID: ITAX_HUMAN
Immunogen Region: 146-342
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 146-342 of ITGAX (NP_000878.2).
Immunogen Sequence: PRQEQDIVFLIDGSGSISSR NFATMMNFVRAVISQFQRPS TQFSLMQFSNKFQTHFTFEE FRRSSNPLSLLASVHQLQGF TYTATAIQNVVHRLFHASYG ARRDAAKILIVITDGKKEGD SLDYKDVIPMADAAGIIRYA IGVGLAFQNRNSWKELNDIA SKPSQEHIFKVEDFDALKDI QNQLKEKIFAIEGTETT
Tissue Specificity Predominantly expressed in monocytes and granulocytes.
Function Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Protein Name Integrin Alpha-X
Cd11 Antigen-Like Family Member C
Leu M5
Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain
Leukocyte Adhesion Receptor P150 -95
Cd Antigen Cd11c
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-216083
Reactome: R-HSA-3000178
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-X antibody
Anti-Cd11 Antigen-Like Family Member C antibody
Anti-Leu M5 antibody
Anti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibody
Anti-Leukocyte Adhesion Receptor P150 -95 antibody
Anti-Cd Antigen Cd11c antibody
Anti-ITGAX antibody
Anti-CD11C antibody

Information sourced from Uniprot.org