| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : |
Mouse monoclonal antibody anti-Integrin Alpha-8 Cleaved Into-Integrin Alpha-8 Heavy Chain-Integrin Alpha-8 Light Chain is suitable for use in ELISA research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA1983 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Function | Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. |
| Protein Name | Integrin Alpha-8 Cleaved Into - Integrin Alpha-8 Heavy Chain - Integrin Alpha-8 Light Chain |
| Database Links | Reactome: R-HSA-2129379Reactome: R-HSA-216083Reactome: R-HSA-2173789Reactome: R-HSA-3000178Reactome: R-HSA-9830674 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Integrin Alpha-8 Cleaved Into - Integrin Alpha-8 Heavy Chain - Integrin Alpha-8 Light Chain antibodyAnti-ITGA8 antibody |
Information sourced from Uniprot.org
