| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4928RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:10000-1:120000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITGA1 |
| Gene ID: | 3672 |
| Uniprot ID: | ITA1_HUMAN |
| Immunogen Region: | 29-1141 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of human Integrin alpha 1 (ITGA1/CD49a) (NP_852478.1). |
| Immunogen Sequence: | FNVDVKNSMTFSGPVEDMFG YTVQQYENEEGKWVLIGSPL VGQPKNRTGDVYKCPVGRGE SLPCVKLDLPVNTSIPNVTE VKENMTFGSTLVTNPNGGFL ACGPLYAYRCGHLHYTTGIC SDVSPTFQVVNSIAPVQECS TQLDIVIVLDGSNSIYPWDS VTAFLNDLLERMDIGPKQTQ VGIVQYGENVTHEFNLNKYS STEEVLVAAKKIVQRGGRQT MTALGIDTARKEAFTEARG |
| Function | Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. |
| Protein Name | Integrin Alpha-1Cd49 Antigen-Like Family Member ALaminin And Collagen ReceptorVla-1Cd Antigen Cd49a |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000157Reactome: R-HSA-416700Reactome: R-HSA-445355Reactome: R-HSA-447041Reactome: R-HSA-75892 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-1 antibodyAnti-Cd49 Antigen-Like Family Member A antibodyAnti-Laminin And Collagen Receptor antibodyAnti-Vla-1 antibodyAnti-Cd Antigen Cd49a antibodyAnti-ITGA1 antibody |
Information sourced from Uniprot.org
