• Western blot analysis of extracts of various cell lines, using ISYNA1 antibody (STJ111497) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
  • Western blot analysis of various lysates using ISYNA1 Rabbit polyclonal antibody (STJ111497) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-ISYNA1 antibody (1-250) (STJ111497)

SKU:
STJ111497

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ISYNA1 (1-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ISYNA1
Gene ID: 51477
Uniprot ID: INO1_HUMAN
Immunogen Region: 1-250
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ISYNA1 (NP_057452.1).
Immunogen Sequence: MEAAAQFFVESPDVVYGPEA IEAQYEYRTTRVSREGGVLK VHPTSTRFTFRTARQVPRLG VMLVGWGGNNGSTLTAAVLA NRLRLSWPTRSGRKEANYYG SLTQAGTVSLGLDAEGQEVF VPFSAVLPMVAPNDLVFDGW DISSLNLAEAMRRAKVLDWG LQEQLWPHMEALRPRPSVYI PEFIAANQSARADNLIPGSR AQQLEQIRRDIRDFRSSAGL DKVIVLWTANTERFCEVIP
Tissue Specificity Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
Post Translational Modifications Phosphorylation at Ser-279 and Ser-357 may be associated with a decrease in activity.
Function Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Protein Name Inositol-3-Phosphate Synthase 1
Ips 1
Myo-Inositol 1-Phosphate Synthase
Mi-1-P Synthase
Mip Synthase
Hips
Myo-Inositol 1-Phosphate Synthase A1
Hino1
Database Links Reactome: R-HSA-1855183
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Inositol-3-Phosphate Synthase 1 antibody
Anti-Ips 1 antibody
Anti-Myo-Inositol 1-Phosphate Synthase antibody
Anti-Mi-1-P Synthase antibody
Anti-Mip Synthase antibody
Anti-Hips antibody
Anti-Myo-Inositol 1-Phosphate Synthase A1 antibody
Anti-Hino1 antibody
Anti-ISYNA1 antibody
Anti-INO1 antibody

Information sourced from Uniprot.org

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