| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ISYNA1 |
| Gene ID: | 51477 |
| Uniprot ID: | INO1_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ISYNA1 (NP_057452.1). |
| Immunogen Sequence: | MEAAAQFFVESPDVVYGPEA IEAQYEYRTTRVSREGGVLK VHPTSTRFTFRTARQVPRLG VMLVGWGGNNGSTLTAAVLA NRLRLSWPTRSGRKEANYYG SLTQAGTVSLGLDAEGQEVF VPFSAVLPMVAPNDLVFDGW DISSLNLAEAMRRAKVLDWG LQEQLWPHMEALRPRPSVYI PEFIAANQSARADNLIPGSR AQQLEQIRRDIRDFRSSAGL DKVIVLWTANTERFCEVIP |
| Tissue Specificity | Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon. |
| Post Translational Modifications | Phosphorylation at Ser-279 and Ser-357 may be associated with a decrease in activity. |
| Function | Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds. |
| Protein Name | Inositol-3-Phosphate Synthase 1Ips 1Myo-Inositol 1-Phosphate SynthaseMi-1-P SynthaseMip SynthaseHipsMyo-Inositol 1-Phosphate Synthase A1Hino1 |
| Database Links | Reactome: R-HSA-1855183 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Inositol-3-Phosphate Synthase 1 antibodyAnti-Ips 1 antibodyAnti-Myo-Inositol 1-Phosphate Synthase antibodyAnti-Mi-1-P Synthase antibodyAnti-Mip Synthase antibodyAnti-Hips antibodyAnti-Myo-Inositol 1-Phosphate Synthase A1 antibodyAnti-Hino1 antibodyAnti-ISYNA1 antibodyAnti-INO1 antibody |
Information sourced from Uniprot.org
