| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
IRX3 |
| Gene ID: |
79191 |
| Uniprot ID: |
IRX3_HUMAN |
| Immunogen Region: |
50-150 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IRX3 (NP_077312.2). |
| Immunogen Sequence: |
SNVLSSVYGAPYAAAAAAAA AQGYGAFLPYAAELPIFPQL GAQYELKDSPGVQHPAAAAA FPHPHPAFYPYGQYQFGDPS RPKNATRESTSTLKAWLNEH R |
| Function | Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism. |
| Protein Name | Iroquois-Class Homeodomain Protein Irx-3Homeodomain Protein Irxb1Iroquois Homeobox Protein 3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Iroquois-Class Homeodomain Protein Irx-3 antibodyAnti-Homeodomain Protein Irxb1 antibodyAnti-Iroquois Homeobox Protein 3 antibodyAnti-IRX3 antibodyAnti-IRXB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
