• Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-MUM1 (ABT080) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: DaudiPredicted band size: 52kDaObserved band size: 52kDa
  • Human colon tissue was stained with Anti-MUM1 (ABT080) Antibody
  • Human diffuse large B-cell lymphoma tissue was stained with Anti-MUM1 (ABT080) Antibody
  • Human diffuse large B-cell lymphoma tissue was stained with Anti-MUM1 (ABT080) Antibody
  • Human tonsil tissue was stained with Anti-MUM1 (ABT080) Antibody
  • Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-MUM1 (ABT080) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: DaudiPredicted band size: 52kDaObserved band size: 52kDa

Anti-IRF4 antibody (350-451 aa) [ABT080] (STJ197173)

SKU:
STJ197173

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/WB/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Interferon regulatory factor 4 (350-451 aa) is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT080
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
WB 1:200-1000
IF 1:100-500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IRF4
Gene ID: 3662
Uniprot ID: IRF4_HUMAN
Immunogen Region: 350-451 aa
Specificity: The antibody can specifically recognize human MUM1 protein.
Immunogen: Synthesized peptide derived from the human MUM1 at the amino acid range 350-451
Post Translational Modifications Phosphorylation by ROCK2 regulates IL-17 and IL-21 production.
Function Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Protein Name Interferon Regulatory Factor 4
Irf-4
Lymphocyte-Specific Interferon Regulatory Factor
Lsirf
Multiple Myeloma Oncogene 1
Nf-Em5
Database Links Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Reactome: R-HSA-909733
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Interferon Regulatory Factor 4 antibody
Anti-Irf-4 antibody
Anti-Lymphocyte-Specific Interferon Regulatory Factor antibody
Anti-Lsirf antibody
Anti-Multiple Myeloma Oncogene 1 antibody
Anti-Nf-Em5 antibody
Anti-IRF4 antibody
Anti-MUM1 antibody

Information sourced from Uniprot.org

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