| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-IRAK3-Mouse (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000. WB: Approx 65-70kDa band observed in Rat Liver lysates, and in preliminary testing of Rat Adrenal Gland lysate (calculated MW of 69.0kDa according to Rat, NP_001101571.1 and 67.8kDa accord |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Immunogen Region: | Internal |
| Accession Number: | NP_082955.2 |
| Immunogen Sequence: | GHSYGSKPMEKR |
| Function | Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. |
| Protein Name | Interleukin-1 Receptor-Associated Kinase 3 Irak-3 Il-1 Receptor-Associated Kinase M Irak-M |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Associated Kinase 3 antibody Anti-Irak-3 antibody Anti-Il-1 Receptor-Associated Kinase M antibody Anti-Irak-M antibody Anti-Irak3 antibody |
Information sourced from Uniprot.org