• Immunohistochemistry analysis of paraffin-embedded rat kidney using IRAK2 Rabbit monoclonal antibody (STJ11102125) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using IRAK2 Rabbit monoclonal antibody (STJ11102125) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-IRAK2 antibody (50-250) [S5MR] (STJ11102125)

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STJ11102125

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-IRAK2 (50-250) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S5MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IRAK2
Gene ID: 3656
Uniprot ID: IRAK2_HUMAN
Immunogen Region: 50-250
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-250 of human IRAK2 (O43187).
Immunogen Sequence: RVQGVSITRELLWWWGMRQA TVQQLVDLLCRLELYRAAQI ILNWKPAPEIRCPIPAFPDS VKPEKPLAASVRKAEDEQEE GQPVRMATFPGPGSSPARAH QPAFLQPPEEDAPHSLRSDL PTSSDSKDFSTSIPKQEKLL SLAGDSLFWSEADVVQATDD FNQNRKISQGTFADVYRGHR HGKPFVFKKLRETACSSPGS I
Tissue Specificity Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Function Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Protein Name Interleukin-1 Receptor-Associated Kinase-Like 2
Irak-2
Database Links Reactome: R-HSA-166058
Reactome: R-HSA-168638
Reactome: R-HSA-445989
Reactome: R-HSA-450302
Reactome: R-HSA-450321
Reactome: R-HSA-9020702
Reactome: R-HSA-937042
Reactome: R-HSA-937072
Reactome: R-HSA-9692916
Reactome: R-HSA-9705671
Reactome: R-HSA-975138
Reactome: R-HSA-975155
Reactome: R-HSA-975163
Reactome: R-HSA-975871
Alternative Antibody Names Anti-Interleukin-1 Receptor-Associated Kinase-Like 2 antibody
Anti-Irak-2 antibody
Anti-IRAK2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance