| Host: | Rabbit |
| Applications: | WB/IHC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification: | Affinity purification |
| Concentration: | 0.4 mg/mL |
| Dilution Range: | WB 1:500-1:2000, IHC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | IRAK1BP1 |
| Gene ID: | 134728 |
| Uniprot ID: | IKBP1_HUMAN |
| Immunogen: | Recombinant protein of human IRAK1BP1 |
| Post Translational Modifications | Phosphorylation at Ser-56 and/or Ser-62 is required for full activity. Phosphorylated on at least one of Ser-235, Thr-237, Ser-242 and Thr-247 upon TNF-alpha activation, which favors nuclear translocation. |
| Function | Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity. |
| Protein Name | Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1Irak1-Binding Protein 1 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 1 antibodyAnti-Irak1-Binding Protein 1 antibodyAnti-IRAK1BP1 antibody |
Information sourced from Uniprot.org