Anti-IQCB1 antibody (431-480) (STJ94403)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480
General Information
| Short Description | Rabbit polyclonal anti-IQ calmodulin-binding motif-containing protein 1 (431-480) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IQCB1 |
| Gene ID | 9657 |
| Uniprot ID | IQCB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480 |
| Immunogen Region | 431-480 |
| Specificity | Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein. |
Additional Info
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. |
| Function | Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6. |
| Protein Name | Iq Calmodulin-Binding Motif-Containing Protein 1Nephrocystin-5P53 And Dna Damage-Regulated Iq Motif ProteinPiq |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleLocalization To The Centrosome Depends On The Interaction With Cep290/Nphp6 |
| Alternative Antibody Names | Anti-Iq Calmodulin-Binding Motif-Containing Protein 1 antibodyAnti-Nephrocystin-5 antibodyAnti-P53 And Dna Damage-Regulated Iq Motif Protein antibodyAnti-Piq antibodyAnti-IQCB1 antibodyAnti-KIAA0036 antibodyAnti-NPHP5 antibodyAnti-OK antibodyAnti-SW-cl.85 antibody |
Information sourced from Uniprot.org