| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IQ calmodulin-binding motif-containing protein 1 (431-480) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IQCB1 |
| Gene ID: |
9657 |
| Uniprot ID: |
IQCB1_HUMAN |
| Immunogen Region: |
431-480 |
| Specificity: |
Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480 |
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. |
| Function | Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6. |
| Protein Name | Iq Calmodulin-Binding Motif-Containing Protein 1Nephrocystin-5P53 And Dna Damage-Regulated Iq Motif ProteinPiq |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleLocalization To The Centrosome Depends On The Interaction With Cep290/Nphp6 |
| Alternative Antibody Names | Anti-Iq Calmodulin-Binding Motif-Containing Protein 1 antibodyAnti-Nephrocystin-5 antibodyAnti-P53 And Dna Damage-Regulated Iq Motif Protein antibodyAnti-Piq antibodyAnti-IQCB1 antibodyAnti-KIAA0036 antibodyAnti-NPHP5 antibodyAnti-OK antibodyAnti-SW-cl.85 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
