Anti-Interleukin 6 antibody [10C12] (STJ16101753)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenA prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule
STJ16101753-1
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General Information

Short DescriptionMouse monoclonal anti-Interleukin 6 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID10C12
IsotypeIgG2a
ConjugationUnconjugated
Dilution RangeIHC-P 1:50
FormulationTissue culture supernatant with 15mM Sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenA prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule

Additional Info

Background IL-6 is a multifunctional cytokine that is secreted by both lymphoid and non-lymphoid cells. It plays a key role in immune responses, hematopoiesis and is an important cytokine in cell proliferation and differentiation. It may also play an important role as an autocrine growth factor in metastatic prostate cancer. IL-6 has been reported to play a role in secretion or release of pituitary hormone in pituitary hormone secreting cells and adenomas. In addition, IL-6 has been suggested to have a trophic effect in nerve cells and to have a direct pathogenic role in CNS disorders. There are an increasing number of reports that cytokines of the IL-6 family play an important regulatory role in heart physiology.

Information sourced from Uniprot.org

Citations

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