Anti-Interleukin 6 antibody [10C12] (STJ16101753)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenA prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule
General Information
| Short Description | Mouse monoclonal anti-Interleukin 6 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 10C12 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | IHC-P 1:50 |
| Formulation | Tissue culture supernatant with 15mM Sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | A prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule |
Additional Info
| Background | IL-6 is a multifunctional cytokine that is secreted by both lymphoid and non-lymphoid cells. It plays a key role in immune responses, hematopoiesis and is an important cytokine in cell proliferation and differentiation. It may also play an important role as an autocrine growth factor in metastatic prostate cancer. IL-6 has been reported to play a role in secretion or release of pituitary hormone in pituitary hormone secreting cells and adenomas. In addition, IL-6 has been suggested to have a trophic effect in nerve cells and to have a direct pathogenic role in CNS disorders. There are an increasing number of reports that cytokines of the IL-6 family play an important regulatory role in heart physiology. |
Information sourced from Uniprot.org