Anti-Insulin Receptor Related Protein antibody [R86-8S-7] (STJA0035472)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Insulin Receptor R
General Information
| Short Description | Rabbit monoclonal anti-Insulin Receptor Related Protein for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R86-8S-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | INSRR |
| Gene ID | 3645 |
| Uniprot ID | INSRR_HUMAN |
| Immunogen | A synthesized peptide derived from human Insulin Receptor R |
Additional Info
| Post Translational Modifications | Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5. |
| Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
| Protein Name | Insulin Receptor-Related ProteinIrrIr-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Insulin Receptor-Related Protein antibodyAnti-Irr antibodyAnti-Ir-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain antibodyAnti-INSRR antibodyAnti-IRR antibody |
Information sourced from Uniprot.org