| Host: | Rabbit |
| Applications: | WB/IHC-P |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Insulin Receptor Related Protein for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R86-8S-7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:100-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | INSRR |
| Gene ID: | 3645 |
| Uniprot ID: | INSRR_HUMAN |
| Immunogen: | A synthesized peptide derived from human Insulin Receptor R |
| Post Translational Modifications | Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5. |
| Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
| Protein Name | Insulin Receptor-Related ProteinIrrIr-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Insulin Receptor-Related Protein antibodyAnti-Irr antibodyAnti-Ir-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain antibodyAnti-INSRR antibodyAnti-IRR antibody |
Information sourced from Uniprot.org
