| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-INSRR (747-921) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INSRR |
| Gene ID: |
3645 |
| Uniprot ID: |
INSRR_HUMAN |
| Immunogen Region: |
747-921 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 747-921 of human INSRR (NP_055030.1). |
| Immunogen Sequence: |
AAGPLRLGGNSSDFEIQEDK VPRERAVLSGLRHFTEYRID IHACNHAAHTVGCSAATFVF ARTMPHREADGIPGKVAWEA SSKNSVLLRWLEPPDPNGLI LKYEIKYRRLGEEATVLCVS RLRYAKFGGVHLALLPPGNY SARVRATSLAGNGSWTDSVA FYILGPEEEDAGGLH |
| Post Translational Modifications | Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5. |
| Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
| Protein Name | Insulin Receptor-Related ProteinIrrIr-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Insulin Receptor-Related Protein antibodyAnti-Irr antibodyAnti-Ir-Related Receptor Cleaved Into - Insulin Receptor-Related Protein Alpha Chain - Insulin Receptor-Related Protein Beta Chain antibodyAnti-INSRR antibodyAnti-IRR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
