Host: |
Rabbit |
Applications: |
IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-INSL3 (1-131) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IHC-P 1:50-1:100IF/ICC 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
INSL3 |
Gene ID: |
3640 |
Uniprot ID: |
INSL3_HUMAN |
Immunogen Region: |
1-131 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human INSL3 (NP_005534.2). |
Immunogen Sequence: |
MDPRLPAWALVLLGPALVFA LGPAPTPEMREKLCGHHFVR ALVRVCGGPRWSTEARRPAT GGDRELLQWLERRHLLHGLV ADSNLTLGPGLQPLPQTSHH HRHHRAAATNPARYCCLSGC TQQDLLTLCPY |
Tissue Specificity | Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast. |
Function | Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor. |
Protein Name | Insulin-Like 3Leydig Insulin-Like PeptideLey-I-LRelaxin-Like Factor Cleaved Into - Insulin-Like 3 B Chain - Insulin-Like 3 A Chain |
Database Links | Reactome: R-HSA-418555Reactome: R-HSA-444821 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Insulin-Like 3 antibodyAnti-Leydig Insulin-Like Peptide antibodyAnti-Ley-I-L antibodyAnti-Relaxin-Like Factor Cleaved Into - Insulin-Like 3 B Chain - Insulin-Like 3 A Chain antibodyAnti-INSL3 antibodyAnti-RLF antibodyAnti-RLNL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance