• Immunohistochemistry of paraffin-embedded human prostate using INSL3 antibody (STJ28295) at dilution of 1:100 (40x lens).

Anti-INSL3 antibody (1-131) (STJ28295)

SKU:
STJ28295

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Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-INSL3 (1-131) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:100
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: INSL3
Gene ID: 3640
Uniprot ID: INSL3_HUMAN
Immunogen Region: 1-131
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human INSL3 (NP_005534.2).
Immunogen Sequence: MDPRLPAWALVLLGPALVFA LGPAPTPEMREKLCGHHFVR ALVRVCGGPRWSTEARRPAT GGDRELLQWLERRHLLHGLV ADSNLTLGPGLQPLPQTSHH HRHHRAAATNPARYCCLSGC TQQDLLTLCPY
Tissue Specificity Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast.
Function Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Protein Name Insulin-Like 3
Leydig Insulin-Like Peptide
Ley-I-L
Relaxin-Like Factor Cleaved Into - Insulin-Like 3 B Chain - Insulin-Like 3 A Chain
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-444821
Cellular Localisation Secreted
Alternative Antibody Names Anti-Insulin-Like 3 antibody
Anti-Leydig Insulin-Like Peptide antibody
Anti-Ley-I-L antibody
Anti-Relaxin-Like Factor Cleaved Into - Insulin-Like 3 B Chain - Insulin-Like 3 A Chain antibody
Anti-INSL3 antibody
Anti-RLF antibody
Anti-RLNL antibody

Information sourced from Uniprot.org

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