| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein inscuteable homolog is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | INSC |
| Gene ID: | 387755 |
| Uniprot ID: | INSC_HUMAN |
| Specificity: | This antibody detects endogenous levels of INSC at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human INSC |
| Function | May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. |
| Protein Name | Protein Inscuteable Homolog |
| Cellular Localisation | CytoplasmCell CortexUniformly Distributed In The Cytoplasm During InterphaseDuring MetaphaseDetected In The Cell CortexAdjacent To The Mitotic Spindle Poles |
| Alternative Antibody Names | Anti-Protein Inscuteable Homolog antibodyAnti-INSC antibody |
Information sourced from Uniprot.org