Anti-INMT antibody [R02-8B2] (STJA0034473)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human INMT
General Information
| Short Description | Rabbit monoclonal anti-INMT for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-8B2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | INMT |
| Gene ID | 11185 |
| Uniprot ID | INMT_HUMAN |
| Immunogen | A synthetic peptide of human INMT |
Additional Info
| Tissue Specificity | Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. |
| Function | Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds. |
| Protein Name | Indolethylamine N-MethyltransferaseIndolamine N-MethyltransferaseAromatic Alkylamine N-MethyltransferaseAmine N-MethyltransferaseArylamine N-MethyltransferaseThioether S-MethyltransferaseTemt |
| Database Links | Reactome: R-HSA-2408552 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Indolethylamine N-Methyltransferase antibodyAnti-Indolamine N-Methyltransferase antibodyAnti-Aromatic Alkylamine N-Methyltransferase antibodyAnti-Amine N-Methyltransferase antibodyAnti-Arylamine N-Methyltransferase antibodyAnti-Thioether S-Methyltransferase antibodyAnti-Temt antibodyAnti-INMT antibody |
Information sourced from Uniprot.org