| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Indolethylamine N-Methyltransferase (1-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4136RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INMT |
| Gene ID: |
11185 |
| Uniprot ID: |
INMT_HUMAN |
| Immunogen Region: |
1-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human TEMT (O95050). |
| Immunogen Sequence: |
MKGGFTGGDEYQKHFLPRDY LATYYSFDGSPSPEAEMLKF NLECLHKTFGPGGLQGDTLI DIGSGPTIYQVLAACDSFQD ITLSDFTDRNREELEKWLKK EPGAYDWTPAVKFACELEGN SGRWEEKEEKLRAAVKRVLK CDVHLGNPLA |
| Tissue Specificity | Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. |
| Function | Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds. |
| Protein Name | Indolethylamine N-MethyltransferaseIndolamine N-MethyltransferaseAromatic Alkylamine N-MethyltransferaseAmine N-MethyltransferaseArylamine N-MethyltransferaseThioether S-MethyltransferaseTemt |
| Database Links | Reactome: R-HSA-2408552 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Indolethylamine N-Methyltransferase antibodyAnti-Indolamine N-Methyltransferase antibodyAnti-Aromatic Alkylamine N-Methyltransferase antibodyAnti-Amine N-Methyltransferase antibodyAnti-Arylamine N-Methyltransferase antibodyAnti-Thioether S-Methyltransferase antibodyAnti-Temt antibodyAnti-INMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
