Background | Inhibins and activins are members of the transforming growth factor beta (TGF Beta ) family of cytokines. Inhibins are heterodimers consisting of a common Alpha-subunit linked to either a Beta A subunit ( Alpha-Beta A, forming inhibin A) or a Beta B subunit ( Alpha-Beta B, forming inhibin B). Activins share the Beta-subunit with the inhibins and may be homo or heterodimers of Beta-subunits forming activin A ( Beta A-Beta A) , activin AB ( Beta A-Beta B) or activin B ( Beta B-Beta B). The expression of the Alpha-subunit, and therefore of inhibins appears to be more restricted than that of the Beta-subunit, and therefore of activins. Inhibins and activins play a role in the regulation of pituitary follicle stimulating hormone (FSH) secretion. |
Information sourced from Uniprot.org