| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | INA |
| Gene ID: | 9118 |
| Uniprot ID: | AINX_HUMAN |
| Immunogen Region: | 350-450 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Alpha Internexin (Q16352). |
| Immunogen Sequence: | EVAGYQDSIGQLENDLRNTK SEMARHLREYQDLLNVKMAL DIEIAAYRKLLEGEETRFST SGLSISGLNPLPNPSYLLPP RILSATTSKVSSTGLSLKKE E |
| Tissue Specificity | Found predominantly in adult CNS. |
| Post Translational Modifications | O-glycosylated. |
| Function | Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks. |
| Protein Name | Alpha-InternexinAlpha-Inx66 Kda Neurofilament ProteinNf-66Neurofilament-66Neurofilament 5 |
| Alternative Antibody Names | Anti-Alpha-Internexin antibodyAnti-Alpha-Inx antibodyAnti-66 Kda Neurofilament Protein antibodyAnti-Nf-66 antibodyAnti-Neurofilament-66 antibodyAnti-Neurofilament 5 antibodyAnti-INA antibodyAnti-NEF5 antibody |
Information sourced from Uniprot.org