Anti-IL34 antibody [SAA0396] (STJA0027575)

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STJA0027575
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Interleukin-34 is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0396
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: IL34
Gene ID: 146433
Uniprot ID: IL34_HUMAN
Function Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Protein Name Interleukin-34
Il-34
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9680350
Cellular Localisation Secreted
Alternative Antibody Names Anti-Interleukin-34 antibody
Anti-Il-34 antibody
Anti-IL34 antibody
Anti-C16orf77 antibody

Information sourced from Uniprot.org

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