| Short Description : | Rabbit polyclonal IL2RB (316-431) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL2RB |
| Gene ID: | 3560 |
| Uniprot ID: | IL2RB_HUMAN |
| Immunogen Region: | 316-431 |
| Immunogen Sequence: | GGLAPEISPLEVLERDKVTQ LLLQQDKVPEPASLSSNHSL TSCFTNQGYFFFHLPDALEI EACQVYFTYDPYSEEDPDEG VAGAPTGSSPQPLQPLSGED DAYCTFPSRDDLLLFS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 316-431 of human IL2RB (NP_000869.1). |
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaInterleukin-15 Receptor Subunit BetaP70-75P75Cd Antigen Cd122 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8983432Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Beta antibodyAnti-Il-2 Receptor Subunit Beta antibodyAnti-Il-2r Subunit Beta antibodyAnti-Il-2rb antibodyAnti-High Affinity Il-2 Receptor Subunit Beta antibodyAnti-Interleukin-15 Receptor Subunit Beta antibodyAnti-P70-75 antibodyAnti-P75 antibodyAnti-Cd Antigen Cd122 antibodyAnti-IL2RB antibodyAnti-IL15RB antibody |
Information sourced from Uniprot.org
