Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | IL2RB |
Gene ID: | 3560 |
Uniprot ID: | IL2RB_HUMAN |
Immunogen Region: | 316-431 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 316-431 of human IL2RB (NP_000869.1). |
Immunogen Sequence: | GGLAPEISPLEVLERDKVTQ LLLQQDKVPEPASLSSNHSL TSCFTNQGYFFFHLPDALEI EACQVYFTYDPYSEEDPDEG VAGAPTGSSPQPLQPLSGED DAYCTFPSRDDLLLFS |
Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaInterleukin-15 Receptor Subunit BetaP70-75P75Cd Antigen Cd122 |
Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8983432Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Beta antibodyAnti-Il-2 Receptor Subunit Beta antibodyAnti-Il-2r Subunit Beta antibodyAnti-Il-2rb antibodyAnti-High Affinity Il-2 Receptor Subunit Beta antibodyAnti-Interleukin-15 Receptor Subunit Beta antibodyAnti-P70-75 antibodyAnti-P75 antibodyAnti-Cd Antigen Cd122 antibodyAnti-IL2RB antibodyAnti-IL15RB antibody |
Information sourced from Uniprot.org