• Western blot analysis of lysate from 293 cells, using IL24 Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Western blot analysis of 293 cells using MDA-7 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-IL24 antibody (131-180 aa) (STJ96776)

SKU:
STJ96776

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Interleukin-24 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL24
Gene ID: 11009
Uniprot ID: IL24_HUMAN
Immunogen Region: 131-180 aa
Specificity: MDA-7 Polyclonal Antibody detects endogenous levels of MDA-7 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL24 at the amino acid range 131-180
Post Translational Modifications Glycosylated. Ubiquitination at Lys-122 promotes proteasomal degradation.
Function Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I intereferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2.
Protein Name Interleukin-24
Il-24
Melanoma Differentiation-Associated Gene 7 Protein
Mda-7
Suppression Of Tumorigenicity 16 Protein
Database Links Reactome: R-HSA-8854691
Cellular Localisation Secreted
Alternative Antibody Names Anti-Interleukin-24 antibody
Anti-Il-24 antibody
Anti-Melanoma Differentiation-Associated Gene 7 Protein antibody
Anti-Mda-7 antibody
Anti-Suppression Of Tumorigenicity 16 Protein antibody
Anti-IL24 antibody
Anti-MDA7 antibody
Anti-ST16 antibody

Information sourced from Uniprot.org

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