Anti-IL23R nanobody [SAA1299] (STJN000282)

Anti-IL23R nanobody [SAA1299] (STJN000282)

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STJN000282
$510.98 - $2,203.88
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA/FC/SPR
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Interleukin-23 Receptor is suitable for use in ELISA, Flow Cytometry and SPR research applications.
Clonality : Monoclonal
Clone ID : SAA1299
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: IL23R
Gene ID: 149233
Uniprot ID: IL23R_HUMAN
Post Translational Modifications Phosphorylated in response to IL23.
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Protein Name Interleukin-23 Receptor
Il-23 Receptor
Il-23r
Database Links Reactome: R-HSA-6785807
Reactome: R-HSA-9020933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Nanobody Names Anti-Interleukin-23 Receptor nanobody
Anti-Il-23 Receptor nanobody
Anti-Il-23r nanobody
Anti-IL23R nanobody

Information sourced from Uniprot.org

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