| Short Description : | Mouse monoclonal Interleukin-1 Receptor Antagonist Protein (Arg26-Glu177) antibody for use in ELISA, IHC and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/IHC/WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Clonality : | Monoclonal |
| Clone ID : | 1A170 |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Protein A/G purified from cell culture supernatant |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Gene Symbol: | IL1RN |
| Gene ID: | 3557 |
| Uniprot ID: | IL1RA_HUMAN |
| Immunogen: | E coli-derived recombinant Human IL1RN/IL-1ra/IL1F3 (Arg26-Glu177) |
| Immunogen Region: | Arg26-Glu177 |
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor Antagonist Protein antibodyAnti-Il-1rn antibodyAnti-Il-1ra antibodyAnti-Irap antibodyAnti-Icil-1ra antibodyAnti-Il1 Inhibitor antibodyAnti-Anakinra antibodyAnti-IL1RN antibodyAnti-IL1F3 antibodyAnti-IL1RA antibody |
Information sourced from Uniprot.org