Anti-IL1RAPL1 antibody (340-420 aa) (STJ192329)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 340-420
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-1 receptor accessory protein-like 1 (340-420 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL1RAPL1 |
| Gene ID | 11141 |
| Uniprot ID | IRPL1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 340-420 |
| Immunogen Region | 340-420 aa |
| Specificity | IRPL1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD. |
| Protein Name | Interleukin-1 Receptor Accessory Protein-Like 1Il-1-Rapl-1Il-1rapl-1Il1rapl-1Oligophrenin-4Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2Tigirr-2X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 |
| Database Links | Reactome: R-HSA-388844Reactome: R-HSA-9007892 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCell ProjectionAxonDendriteMay Localize To The Cell Body And Growth Cones Of Dendrite-Like Processes |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor Accessory Protein-Like 1 antibodyAnti-Il-1-Rapl-1 antibodyAnti-Il-1rapl-1 antibodyAnti-Il1rapl-1 antibodyAnti-Oligophrenin-4 antibodyAnti-Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2 antibodyAnti-Tigirr-2 antibodyAnti-X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 antibodyAnti-IL1RAPL1 antibodyAnti-OPHN4 antibody |
Information sourced from Uniprot.org