Function | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD. |
Protein Name | Interleukin-1 Receptor Accessory Protein-Like 1Il-1-Rapl-1Il-1rapl-1Il1rapl-1Oligophrenin-4Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2Tigirr-2X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 |
Database Links | Reactome: R-HSA-388844Reactome: R-HSA-9007892 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCell ProjectionAxonDendriteMay Localize To The Cell Body And Growth Cones Of Dendrite-Like Processes |
Alternative Antibody Names | Anti-Interleukin-1 Receptor Accessory Protein-Like 1 antibodyAnti-Il-1-Rapl-1 antibodyAnti-Il-1rapl-1 antibodyAnti-Il1rapl-1 antibodyAnti-Oligophrenin-4 antibodyAnti-Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2 antibodyAnti-Tigirr-2 antibodyAnti-X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 antibodyAnti-IL1RAPL1 antibodyAnti-OPHN4 antibody |
Information sourced from Uniprot.org