Anti-IL13RA2 antibody (96-107) (STJ73149)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-IL13RA2 (96-107) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 50+60kDa bands observed in lysates of cell line HeLa (calculated MW of 44.2kDa according to NP_000631.1). The observed molecular weight corresponds to earlier findings in liter |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | IL13RA2 |
| Gene ID | 3598 |
| Uniprot ID | I13R2_HUMAN |
| Accession Number | NP_000631.1 |
| Immunogen Region | 96-107 |
| Immunogen Sequence | DLNKGIEAKIHT |
Additional Info
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-2Il-13 Receptor Subunit Alpha-2Il-13r Subunit Alpha-2Il-13r-Alpha-2Il-13ra2Interleukin-13-Binding ProteinCd Antigen Cd213a2 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13r Subunit Alpha-2 antibodyAnti-Il-13r-Alpha-2 antibodyAnti-Il-13ra2 antibodyAnti-Interleukin-13-Binding Protein antibodyAnti-Cd Antigen Cd213a2 antibodyAnti-IL13RA2 antibodyAnti-IL13R antibody |
Information sourced from Uniprot.org