| Post Translational Modifications | Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13. |
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-2Il-13 Receptor Subunit Alpha-2Il-13r Subunit Alpha-2Il-13r-Alpha-2Il-13ra2Interleukin-13-Binding ProteinCd Antigen Cd213a2 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13r Subunit Alpha-2 antibodyAnti-Il-13r-Alpha-2 antibodyAnti-Il-13ra2 antibodyAnti-Interleukin-13-Binding Protein antibodyAnti-Cd Antigen Cd213a2 antibodyAnti-IL13RA2 antibodyAnti-IL13R antibody |
Information sourced from Uniprot.org
