Post Translational Modifications | N-glycosylated. |
Function | Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. |
Protein Name | Interleukin-31 Receptor Subunit AlphaIl-31 Receptor Subunit AlphaIl-31r Subunit AlphaIl-31r-AlphaIl-31raGlm-RMglm-RGp130-Like Monocyte ReceptorGp130-Like ReceptorNovel Cytokine Receptor 10Nr10Zcytor17 |
Database Links | Reactome: R-MMU-6788467 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresynaptic Cell MembraneCell ProjectionAxon |
Alternative Antibody Names | Anti-Interleukin-31 Receptor Subunit Alpha antibodyAnti-Il-31 Receptor Subunit Alpha antibodyAnti-Il-31r Subunit Alpha antibodyAnti-Il-31r-Alpha antibodyAnti-Il-31ra antibodyAnti-Glm-R antibodyAnti-Mglm-R antibodyAnti-Gp130-Like Monocyte Receptor antibodyAnti-Gp130-Like Receptor antibodyAnti-Novel Cytokine Receptor 10 antibodyAnti-Nr10 antibodyAnti-Zcytor17 antibodyAnti-Il31ra antibodyAnti-Glmr antibody |
Information sourced from Uniprot.org