| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | Il2rb |
| Gene ID: | 16185 |
| Uniprot ID: | IL2RB_MOUSE |
| Immunogen Region: | 27-235 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-235 of mouse IL-2RB (NP_032394.1). |
| Immunogen Sequence: | AVKNCSHLECFYNSRANVSC MWSHEEALNVTTCHVHAKSN LRHWNKTCELTLVRQASWAC NLILGSFPESQSLTSVDLLD INVVCWEEKGWRRVKTCDFH PFDNLRLVAPHSLQVLHIDT QRCNISWKVSQVSHYIEPYL EFEARRRLLGHSWEDASVLS LKQRQQWLFLEMLIPSTSYE VQVRVKAQRNNTGTWSPWSQ PLTFRTRPA |
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaP70-75Cd Antigen Cd122 |
| Database Links | Reactome: R-MMU-5673001Reactome: -MMU-8983432Reactome: -MMU-9020558Reactome: -MMU-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Surface |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Beta antibodyAnti-Il-2 Receptor Subunit Beta antibodyAnti-Il-2r Subunit Beta antibodyAnti-Il-2rb antibodyAnti-High Affinity Il-2 Receptor Subunit Beta antibodyAnti-P70-75 antibodyAnti-Cd Antigen Cd122 antibodyAnti-Il2rb antibody |
Information sourced from Uniprot.org
